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濱松多孔氧化鋁制作的輔助離子化基板DIUTHAME（Desorption Ionization Using Through Hole Alumina MEmbrane），可大幅縮減質(zhì)譜成像分析時(shí)待測(cè)樣品進(jìn)行離子化所需的前期處理的時(shí)間。
只要將本產(chǎn)品放置在待測(cè)樣品上，就能完成質(zhì)量分析的前期處理，與目前主要的離子化方法之一基質(zhì)輔助激光解析電離（Matrix-Assisted Laser Desorption/Ionization、下面簡(jiǎn)稱(chēng)MALDI）方法相比，它將前期處理時(shí)間縮短到十分之一。因此可以用在市場(chǎng)上已有的MALDI-TOF-MS設(shè)備，主要面向目前正在使用MALDI-TOF-MS設(shè)備的制藥、工業(yè)領(lǐng)域的國(guó)內(nèi)外企業(yè)以及大學(xué)研究人員。
A13331-18-2通道的有效面積為Φ18mm。（大面積成像專(zhuān)用）
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產(chǎn)品特點(diǎn)
● 無(wú)基質(zhì)噪聲
● 可縮短預(yù)處理時(shí)間，并實(shí)現(xiàn)高重復(fù)性測(cè)量
● 擴(kuò)大質(zhì)譜成像范圍的印跡法
DIUTHAME與傳統(tǒng)MALDI的區(qū)別
應(yīng)用舉例
| Frozen chicken | MS imaging of a Frozen chicken using blotting method [1.0 MB/PDF] | A13331-18-2B | |
| Chocolate | MS imaging of a chocolate [0.8 MB/PDF] | A13331-5019-1 | |
| fresh strawberry | MS imaging of a fresh sttrawberry using blotting method [0.7 MB/PDF] | Prototype | |
| Mouse brain | DIUTHAME MS imaging of a mouse brain [0.8 MB/PDF] | A13331-18-2， A13331-5019-1 | |
| Flower petal | MS imaging of flower petal using blotting method [1.0 MB/PDF] | A13331-18-2B | |
| Industrial material | MS imaging of an industrial material using blotting method [0.4 MB/PDF] | A13331-18-2B | |
| Polymer material | DIUTHAME-MSI of a polymer material by mist extraction method using a humidifier [0.4 MB/PDF] | A13331-18-2 | |
| Black rice | DIUTHAME MS imaging of black rice [0.5 MB/PDF] | A13331-18-2 | |
| Mouse brain using vapor extraction method | DIUTHAME MS imaging for a mouse brain using vapor extraction method [0.7 MB/PDF] | A13331-18-2 | |
| Skin | Skin analysis by MS imaging using blotting method [0.8 MB/PDF] | A13331-18-2B | |
| Slime mold | DIUTHAME-MSI for chemorepellent of slime mold using blotting method [0.9 MB/PDF] | A13331-18-2 |
外形尺寸（單位：mm）
相關(guān)論文
| Yasuhide Naito， Masahiro Kotani， Takayuki Ohmura | Feasibility of Acetylcholinesterase Reaction Assay Monitoring in DIUTHAME-MS | 2020 American Society for Mass Spectrometry. Published by the American Chemical Society. All rights reserved. | |
| Thierry N. J. Fouquet， Hélène Pizzala， Marion Rollet， Delphine Crozet， Pierre Giusti， and Laurence Charles | Mass Spectrometry-Based Analytical Strategy for Comprehensive Molecular Characterization of Biodegradable Poly(lactic-co-glycolic Acid) Copolymers | 2020 American Society for Mass Spectrometry. Published by the American Chemical Society. All rights reserved. | |
| Keiko Kuwata， Kayoko Itou， Masahiro Kotani， Takayuki Ohmura， Yasuhide Naito | DIUTHAME enables matrix‐free mass spectrometry imaging of frozen tissue sections | Rapid Communications in Mass Spectrometry Volume34， Issue9， 15 March 2020 | |
| Hiroaki Sato， Sayaka Nakamura， Thierry Fouquet， Takayuki Ohmura， Masahiro Kotani， Yasuhide Naito | Molecular characterization of polyethylene oxide based oligomers by surface‐assisted laser desorption/ionization mass spectrometry using a through‐hole alumina membrane as active substrate | Rapid Communications in Mass Spectrometry Volume34， Issue5， 15 March 2020 | |
| Hiroaki Sato， Sayaka Nakamura， Thierry N. J. Fouquet， Takayuki Ohmura， Masahiro Kotani， Yasuhide Naito | Simple Pretreatment for the Analysis of Additives and Polymers by Surface-Assisted Laser Desorption/Ionization Mass Spectrometry Using a Through-Hole Alumina Membrane as a Functional Substrate | 2019 American Society for Mass Spectrometry. Published by the American Chemical Society. All rights reserved. | |
| Hirofumi Enomoto， Masahiro Kotani， Takayuki Ohmura | Novel Blotting Method for Mass Spectrometry Imaging of Metabolites in Strawberry Fruit by Desorption/Ionization Using Through Hole Alumina Membrane | Special Issue "Advancement of Mass Spectrometry Imaging for Food Science" | |
| Yasuhide Naito， Masahiro Kotani， Takayuki Ohmura | A novel laser desorption/ionization method using through hole porous alumina membranes | Rapid Communications in Mass Spectrometry | |
| Yasuhide Naito， Masahiro Kotani， Miu Takimoto， Takayuki Ohmura | Establishing better laboratory protocols for desorption ionization using through hole alumina membrane (DIUTHAME)[1.8 MB/PDF] | ASMS 2019 | |
| Hasan Md. Mahmudul， Yasuhide Naito， Mamun Md. Al， Ariful Islam， A s m Waliullah， Takashi K Ito， Mitsutoshi Setou， Masahiro Kotani， Takayuki Ohmura， Shumpei Sato | The combination of DIUTHAME-IMS/FT-ICR conserves high mass accuracy and resolution over the DIUTHAME-IMS/TOFMS in the laser desorption/ionization imaging mass spectrometry[0.8 MB/PDF] | ASMS 2019 | |
| Masahiro Kotani， Miu Takimoto， Takayuki Ohmura， Akira Tashiro， Hirofumi Enomoto， Yasuhide Naito | Development of blotting method using DIUTHAME for imaging MS[3.0 MB/PDF] | ASMS 2019 | |
| Tsuyoshi Hirao， Yasuhide Naito | Combining DIUTHAME and Stigmatic-Type Mass Microscope toward Cellular Scale Imaging Mass Spectrometry[0.8 MB/PDF] | ASMS 2019 |
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